Progressive Resistance Exercise Training for Patients after Treatment for Lung Cancer: The Re-Train Trial

A study of Progressive Resistance Exercise Training for Post-Treatment Lung Cancer Patients

Investigators: Dr. Kerry Courneya, Dr. Dave Fenton, Dr. Gordon Bell, Dr. Linda McCargar

Project Coordinator: Dr. Carolyn Peddle


Patients with lung cancer are routinely treated with different treatments such as surgery, chemotherapy, radiation therapy.  These treatments can cause functional ability to decline due to fatigue, and loss of fitness and lean muscle mass.

Some studies have indicated that exercise (e.g., biking, walking) may improve fitness and quality of life (QOL) following treatment for lung cancer but no studies have looked at resistance exercise (weight training).

Dr. Kerry Courneya and Dr. David Fenton of the Cross Cancer Institute are conducting a study that will examine the feasibility of a progressive resistance exercise training (PRET) program for improving strength, physical functioning, and quality of life in patients with lung cancer who have finished treatment. 

Purpose of the RE-TRAIN Trial

The main purpose of the RE-TRAIN Trial is to determine the feasibility of progressive resistance exercise training in post-treatment lung cancer patients.

In addition, we will be looking at the effects of resistance exercise training on changes in strength, body composition, and physical functioning.

To determine the feasibility of the resistance exercise training, you will be asked to complete a 14-week resistance exercise training program


You are potentially eligible for the RE-TRAIN Trial if you have been diagnosed with:

  • Stage I – IIIb Non-Small Cell Lung Cancer
  • Limited- stage Small-Cell Lung Cancer
  • You have completed treatment

Please ask your oncologist, nurse, or contact the project coordinator  to find out if you are eligible to participate.

What Does Participating In The RE-TRAIN Trial Involve?

If you meet the eligibility requirements and wish to participate in the trial, you will be asked to complete:

    • The completion of a self-administered questionnaire; approximately 30 minutes.
    • Frequency: once before training, once at the end of training
    • These tests involve lifting weights to determine your current strength, and performing tests of functional fitness (for example, walking).
    • Approximately 1 hour in total. Frequency: three times before training, once in the middle of training, and three times at the end of training.
    • Location: Behavioral Medicine Fitness Centre,  Campus
  3. DXA (Body Composition) SCAN
    • This test involves lying on a table as a low-level X-ray passes over you, which will determine your fat mass, muscle mass, and bone density. 
    • Approximately 5 minutes for the DXA scan (30 minutes total)
    • Frequency: once before training, once at the end of training.
    • Location:  Campus

What Happens After I Complete The Assessments?

  • After you have completed the assessments, you will begin exercise training.
  • You will be asked to come to the Behavioural Medicine Fitness Centre for weight training, three times a week for 10-weeks.
  • Training will consist of doing a total body resistance exercise program.
  • Each session should take about one hour.
  • The program will be tailored to your fitness level when you join the study.
  • You will not have to pay to participate in the trial.
    The exercise program, access to our gym, and supervision from a qualified trainer is free
    Parking costs for testing and exercise sessions will be reimbursed

Any Questions?
If you have questions or require further information about the Re-Train trial, please contact the project coordinator, Carolyn Peddle; Phone: (780) 492-2829 or email: